They include number one seed Naomi Osaka; the Japanese ace had to survive a scare though seeing off Anna Blinkova in a 6-4 6-7 (5-7) 6-2 win. Magda Linette is next up for the World Number One on Thursday evening.
Wimbledon champion Simona Halep was also taken the distance by Nicole Gibbs; but claimed a 6-3, 3-6, 6-2 victory in the end. Coco Gauff also continued her brilliant form; the 15 year old though came from a set and a break down to defeated Anastasia Potapova 3-6, 6-2, 6-4.
Bianca Andreescu, the Rogers Cup champion eased past Katie Volynets 6-2, 6-4; she looked impressive at times to begin her US Open campaign.
The Canadian is seen by many as a potential outside bet for the title; despite looking shaky at certain points, she exhibited why on Court 10.
There was some big names heading out though with Garbine Muguruza; losing to Alison Riske 2-6, 6-1, 6-3. Riske will now face off against Jelena Ostapenko in the next round.
Sloane Stephens also fell at the first hurdle in her home tournament. Stephens was beaten; by qualifier Anna Kalinskaya 3-6, 4-6.
Di Lorenzo F. (Usa) | 2 | 77 | 6 | |||||||||
Kudermetova V. (Rus) | 0 | 64 | 2 | |||||||||
Minella M. (Lux) | 0 | 3 | 2 | |||||||||
Bencic B. (Sui) | 2 | 6 | 6 | |||||||||
Allertova D. (Cze) | 0 | 2 | 4 | |||||||||
Kvitova P. (Cze) | 2 | 6 | 6 | |||||||||
Cornet A. (Fra) | 2 | 6 | 6 | |||||||||
Pegula J. (Usa) | 0 | 2 | 3 | |||||||||
Goerges J. (Ger) | 2 | 1 | 6 | 77 | ||||||||
Vikhlyantseva N. (Rus) | 1 | 6 | 1 | 61 | ||||||||
Krunic A. (Srb) | 0 | 3 | 67 | |||||||||
Ostapenko J. (Lat) | 2 | 6 | 79 | |||||||||
Petkovic A. (Ger) | 2 | 6 | 6 | |||||||||
Buzarnescu M. (Rou) | 0 | 3 | 4 | |||||||||
Riske A. (Usa) | 2 | 2 | 6 | 6 | ||||||||
Muguruza G. (Esp) | 1 | 6 | 1 | 3 | ||||||||
Osaka N. (Jpn) | 2 | 6 | 65 | 6 | ||||||||
Blinkova A. (Rus) | 1 | 4 | 77 | 2 | ||||||||
Sharma A. (Aus) | 0 | 3 | 4 | |||||||||
Linette M. (Pol) | 2 | 6 | 6 | |||||||||
Badosa G. P. (Esp) | 0 | 4 | 2 | |||||||||
Bertens K. (Ned) | 2 | 6 | 6 | |||||||||
Volynets K. (Usa) | 0 | 2 | 4 | |||||||||
Andreescu B. V. (Can) | 2 | 6 | 6 | |||||||||
Wang Xiy. (Chn) | 1 | 6 | 2 | 2 | ||||||||
Flipkens K. (Bel) | 2 | 3 | 6 | 6 | ||||||||
Kanepi K. (Est) | 2 | 5 | 77 | 6 | ||||||||
Maria T. (Ger) | 1 | 7 | 64 | 3 | ||||||||
Collins D. R. (Usa) | 2 | 6 | 4 | 6 | ||||||||
Hercog P. (Slo) | 1 | 3 | 6 | 4 | ||||||||
Parmentier P. (Fra) | 0 | 1 | 62 | |||||||||
Pavlyuchenkova A. (Rus) | 2 | 6 | 77 | |||||||||
Kontaveit A. (Est) | 2 | 6 | 6 | |||||||||
Sorribes Tormo S. (Esp) | 0 | 1 | 1 | |||||||||
Townsend T. (Usa) | 2 | 3 | 6 | 6 | ||||||||
Kozlova Kat. (Ukr) | 1 | 6 | 3 | 2 | ||||||||
Halep S. (Rou) | 2 | 6 | 3 | 6 | ||||||||
Gibbs N. (Usa) | 1 | 3 | 6 | 2 | ||||||||
Wozniacki C. (Den) | 2 | 1 | 7 | 6 | ||||||||
Wang Y. (Chn) | 1 | 6 | 5 | 3 | ||||||||
Tomljanovic A. (Aus) | 2 | 1 | 7 | 6 | ||||||||
Bouzkova M. (Cze) | 1 | 6 | 5 | 1 | ||||||||
Mertens E. (Bel) | 2 | 6 | 6 | |||||||||
Teichmann J. B. (Sui) | 0 | 2 | 2 | |||||||||
Potapova A. (Rus) | 1 | 6 | 2 | 4 | ||||||||
Gauff C. (Usa) | 2 | 3 | 6 | 6 | ||||||||
Babos T. (Hun) | 1 | 6 | ||||||||||
Suarez Navarro C. (Esp) | 0 | 2 | ||||||||||
Ahn K. (Usa) | 2 | 7 | 6 | |||||||||
Kuznetsova S. (Rus) | 0 | 5 | 2 | |||||||||
Cirstea S. (Rou) | 2 | 7 | 6 | |||||||||
Siniakova K. (Cze) | 0 | 5 | 2 | |||||||||
Pliskova Kr. (Cze) | 2 | 6 | 6 | |||||||||
Parry D. (Fra) | 0 | 4 | 3 | |||||||||
Bolsova Zadoinov A. (Esp) | 2 | 6 | 0 | 6 | ||||||||
Strycova B. (Cze) | 1 | 3 | 6 | 1 | ||||||||
Hogenkamp R. (Ned) | 0 | 64 | 3 | |||||||||
Vekic D. (Cro) | 2 | 77 | 6 | |||||||||
Putintseva Y. (Kaz) | 2 | 6 | 6 | |||||||||
Brengle M. (Usa) | 0 | 3 | 3 | |||||||||
Sabalenka A. (Blr) | 2 | 3 | 6 | 6 | ||||||||
Azarenka V. (Blr) | 1 | 6 | 3 | 4 | ||||||||
Stephens S. (Usa) | 0 | 3 | 4 | |||||||||
Kalinskaya A. (Rus) | 2 | 6 | 6 |