Murray will take on eighth seed and one of the top young players on the tour in Matteo Berrettini, who gave Rafael Nadal a real test at the recent US Open.
The former World No.1 played two rounds in Zhuhai as he claimed his first senior tour level win since January against Tennys Sandgren.
As well as Murray and Berrettini, the field is headed up by Dominic Thiem. He will take on Richard Gasquet in his first round.
The likes of Karen Khachanov, Grigor Dimitrov who will be aiming for that elusive 300th career win after losing to Alexander Bublik in Chengdu and Andrey Rublev are all also involved.
Alexander Zverev and Stefanos Tsitisipas are also potentially on a collision course. Zverev takes on Frances Tiafoe; while Tsitsipas faces Dusan Lajovic first.
View the draw China Open 2019 in full below: