Usually in Cincinnati, it saw Daniil Medvedev come through the draw last year to become champion; which saw him on his way to a brilliant run to the final of the US Open. He will face a different task though this year; as he is on a potential collision course with World No.1, Novak Djokovic.
They are both in the same half of the draw; but have both received byes through to the next round due to their seeding.
Djokovic is set to begin against either Tommy Paul or a Qualifier; while Daniil Medvedev will face a Qualifier. For the former, the first seeded player he could face is Felix Auger-Aliassime who takes on Georgian ace Nikoloz Basilashvili first up.
Second seed Dominic Thiem has probably been the most active ATP player during lockdown; he will aim utilise that match fitness when he takes on Filip Krajinovic or a qualifier. A tie against Grigor Dimitrov is a third round possibility.
One of the big ties though sees Andy Murray face off against Frances Tiafoe in a tough start to proceedings. If he beats the home hero, Alexander Zverev awaits in his first competitive action of 2020; barring of course the Battle of the Brits during lockdown.
Other ties to look out for include Denis Shapovalov against Marin Cilic, Milos Raonic v Sam Querrey; as well as returning Kevin Anderson taking on Kyle Edmund.